DMSO and fake science

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Pyrrho
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Re: DMSO and fake science

Post by Pyrrho »

robinson wrote: Fri Oct 23, 2020 1:13 am The placebo argument is of course, one of the ways to avoid the evidence from animals. There is zero doubt about the treatment of animals, and animals are not subject to the placebo effect.

This is why I said the many years of treatment of animals will not matter at all. The fake science surrounding DMSO is quite strong.

For example, note that the info on an FDA approved use was just ignored.
In 2009, the first to obtain FDA approval for topological DMSO usage was PENNSAID®, which contains diclofenac in a carrier with 45.5% DMSO
Animal models are a step up from in vitro models. There's a reason why clinical testing using human subjects is necessary for approval of drug therapies. Guess why.

Anyway, for the fans in the bleachers:

https://clinicaltrials.gov/ct2/results? ... ity=&dist=
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robinson
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Re: DMSO and fake science

Post by robinson »

That was/is a very good link.
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robinson
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Re: DMSO and fake science

Post by robinson »

One of those studies is trying to confirm something that I have known about for 36 years
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robinson
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Re: DMSO and fake science

Post by robinson »

Look, I’m not proposing, advising or promoting anyone to do anything, I stopped advocating decades ago, to the point that even if I knew something that could save your life, I wouldn’t say a thing.

When it comes to medical stuff, people are just nuts in the US

Even the mere hint of quackery is enough for the torches and pitchforks to come out, angry mobs to form, and the truth is no defense in these matters.
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robinson
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Re: DMSO and fake science

Post by robinson »

Some things in life, in physics and even medicine are self evident. And some things are impossible to double blind, because it’s really self evident if you are getting the placebo when it comes to anything using DMSO, or just DMSO by itself.

This is a known problem. Nobody who has ever worked with DMSO has any doubt about that problem. Even a small amount is very self evident, it’s literally impossible to not know if DMSO is being used. The goddamn smell, the taste, it’s unforgettable, and it’s almost instant. You apply any to just your skin and you can taste it and smell it right away.

A large amount (more than a few drops) and you reek of it, it just moves through your body so fast, and the sulfurous stink is unbelievable
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robinson
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Re: DMSO and fake science

Post by robinson »

It’s garlic, rotten eggs and some sewer gas all combined. Whatever the fuck you do, don’t put it down a sink where it will sit in the trap. It will smell so fucking bad it’s not a joke. It’s a very powerful solvent, and idiots can easily get sick or die using it with out precautions. Pretty much anything dissolved in DMSO WILL GO RIGHT INTO YOUR BODY, and that can be a very bad thing

SAME FOR ANYTHING ON YOUR SKIN IF YOU GET IT ON YOU
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robinson
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Re: DMSO and fake science

Post by robinson »

Pyrrho wrote: Fri Oct 23, 2020 10:03 pm Animal models are a step up from in vitro models. There's a reason why clinical testing using human subjects is necessary for approval of drug therapies.
Except the most common usage of DMSO was never tested, much less on human subjects.
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Doctor X
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Re: DMSO and fake science

Post by Doctor X »

Some medicine for fools:
Conclusions and clinical importance: A positive response to placebo administration, manifesting as a decrease in seizure frequency, can be observed in epileptic dogs. This is of importance when evaluating open label studies in dogs that aim to assess efficacy of antiepileptic drugs, as the reported results might be overstated. Findings from this study highlight the need for more placebo-controlled trials in veterinary medicine.

K R Muñana, D Zhang, E E Patterson.
Placebo effect in canine epilepsy trials, Vet Intern Med. Jan-Feb 2010;24(1):166-70.
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