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Wikipedia wrote:Towards the end of her life, Hypatia advised Orestes, the Roman prefect of Alexandria, who was in the midst of a political feud with Cyril, the bishop of Alexandria. Rumors spread accusing her of preventing Orestes from reconciling with Cyril and, in March 415 AD, she was murdered by a mob of Christians led by a lector named Peter.
Wikipedia wrote:The Library dwindled during the Roman Period, due to lack of funding and support. Its membership appears to have ceased by the 260s AD. Between 270 and 275 AD, the city of Alexandria saw a rebellion and an imperial counterattack that probably destroyed whatever remained of the Library, if it still existed at that time. The daughter library of the Serapeum may have survived after the main Library's destruction. The Serapeum was vandalized and demolished in 391 AD under a decree issued by Coptic Christian Pope Theophilus of Alexandria, but it does not seem to have housed books at the time and was mainly used as a gathering place for Neoplatonist philosophers following the teachings of Iamblichus.