Wuhan Flu Truth and Big Brother Narratives

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Pyrrho
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Re: Wuhan Flu Truth and Big Brother Narratives

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My guess would be that China's strict measures resulted in a lower rate of virus carriers. Looking at the article...giving it my best shot here, Boss...
Stringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence of infection following the release of restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme between May 14 and June 1, 2020 in Wuhan. All city residents aged six years or older were eligible and 9,899,828 (92.9%) participated. No new symptomatic cases and 300 asymptomatic cases (detection rate 0.303/10,000, 95% CI 0.270–0.339/10,000) were identified. There were no positive tests amongst 1,174 close contacts of asymptomatic cases. 107 of 34,424 previously recovered COVID-19 patients tested positive again (re-positive rate 0.31%, 95% CI 0.423–0.574%). The prevalence of SARS-CoV-2 infection in Wuhan was therefore very low five to eight weeks after the end of lockdown.
The screening took place after the lockdowns were over. 300 asymptomatic cases in a group of 9,899,828 people. The authors conclude that "The prevalence of SARS-CoV-2 infection in Wuhan was therefore very low five to eight weeks after the end of lockdown." which we can see is pretty much true based on the data.

The authors also report:
All asymptomatic positive cases, repositive cases and their close contacts were isolated for at least 2 weeks until the results of nucleic acid testing were negative. None of detected positive cases or their close contacts became symptomatic or newly confirmed with COVID-19 during the isolation period.
Further:
Previous studies have shown that asymptomatic individuals infected with SARS-CoV-2 virus were infectious3, and might subsequently become symptomatic4. Compared with symptomatic patients, asymptomatic infected persons generally have low quantity of viral loads and a short duration of viral shedding, which decrease the transmission risk of SARS-CoV-25. In the present study, virus culture was carried out on samples from asymptomatic positive cases, and found no viable SARS-CoV-2 virus. All close contacts of the asymptomatic positive cases tested negative, indicating that the asymptomatic positive cases detected in this study were unlikely to be infectious.
And...
This study has several limitations that need to be discussed. First, this was a cross-sectional screening programme, and we are unable to assess the changes over time in asymptomatic positive and reoperative results.
There is much more of course and it is subject to discussion and interpretation. I don't know what the other studies are that they refer to, or how the data in those other studies was collected, etc., but IMHO is it premature to conclude from this paper that lockdowns and other precautions are needless.

One could just as easily argue that this shows that strict lockdown measures such as those imposed in China are very effective in throttling the spread of the virus, resulting in a very low number of asymptomatic carriers, and that post-lockdown adherence to protective behaviors further reduces the risk of exposure. Contrasting these results with the continuing surge of infections and hospital overloads in the United States indicates that lesser measures clearly do not "work" with the same efficiency as the strict measured imposed in China.

Also...the conclusion by the Twitter personality that spread of the virus by asymptomatic people is not a matter for concern and that lockdowns, etc. are not needed is an oversimplification that assumes that any given person is "asymptomatic" and is thus not contagious, and that he knows better than other experts and organizations. The asymptomatic people in this study may have been contagious previous to the assessment--the study does indicate that none of their close contacts were carriers--but again, they may have had it and cleared it. Thus it is a limitation to the analysis.

Imma wear a mask and stay home as much as possible, considering that infections continue to rise in my neck of the woods.
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Re: Wuhan Flu Truth and Big Brother Narratives

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Pyrrho wrote: Sat Nov 21, 2020 7:51 pm
Imma wear a mask and stay homo as much as possible
FIFY
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I don’t care if the mask work or not I want people to have to keep wearing them. It keeps their fucking human goo that comes out of their mouth and nose from getting in my car.
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Re: Wuhan Flu Truth and Big Brother Narratives

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robinson wrote: Sat Nov 21, 2020 11:41 pm I don’t care if the mask work or not I want people to have to keep wearing them. It keeps their fucking human goo that comes out of their mouth and nose from getting in my car.
Why don't you just use an extra piece of duct tape?
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Re: Wuhan Flu Truth and Big Brother Narratives

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As a God, you shouldn’t have to ask
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Re: Wuhan Flu Truth and Big Brother Narratives

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FWIW YMMV

https://www.nytimes.com/interactive/202 ... tions.html
Coronavirus cases are rising in almost every U.S. state. But the surge is worst now in places where leaders neglected to keep up forceful virus containment efforts or failed to implement basic measures like mask mandates in the first place, according to a New York Times analysis of data from the University of Oxford.
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Re: Wuhan Flu Truth and Big Brother Narratives

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gnome wrote: Sat Nov 21, 2020 7:11 pm Help me out with this--why does this study find something different from so many other studies about presymptomatic transmission? Where's the disconnect?
It said they were asymptomatic, not presymptomatic. This was after the lockdown. (The difference being that presymptomatic people later go on to develop symptoms. It means the early stage of an infection, while the virus is still cooking up and the immune system hasn't really started to kick in yet. Asymptomatic simply means any person who has no symptoms, and I'm pretty sure that none of these people later developed symptoms, or they would have mentioned that.

It's thought that people who have recovered and are no longer infectious may shed viral particles for some time even after they have fully recovered. These viral particles themselves are not active viruses that could result in a new infection in another host.
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Re: Wuhan Flu Truth and Big Brother Narratives

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FDA has approved emergency use for two monoclonal antibodies for COVID-19 treatment.

https://www.fda.gov/news-events/press-a ... t-covid-19
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Re: Wuhan Flu Truth and Big Brother Narratives

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Trends in County-Level COVID-19 Incidence in Counties With and Without a Mask Mandate — Kansas, June 1–August 23, 2020

Summary

What is already known about this this topic?

Wearing face masks in public spaces reduces the spread of SARS-CoV-2.

What is added by this report?

The governor of Kansas issued an executive order requiring wearing masks in public spaces, effective July 3, 2020, which was subject to county authority to opt out. After July 3, COVID-19 incidence decreased in 24 counties with mask mandates but continued to increase in 81 counties without mask mandates.

What are the implications for public health practice?

Countywide mask mandates appear to have contributed to the mitigation of COVID-19 transmission in mandated counties. Community-level mitigation strategies emphasizing use of masks, physical distancing, staying at home when ill, and enhanced hygiene practices can help reduce the transmission of SARS-CoV-2.
https://www.cdc.gov/mmwr/volumes/69/wr/mm6947e2.htm for the full paper.

How surprising! :roll:
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Re: Wuhan Flu Truth and Big Brother Narratives

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Re: Wuhan Flu Truth and Big Brother Narratives

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VRBAC meeting will be livestreamed on YouTube. Probably your best option. The webcast on the FDA site will be via Adobe Connect and will definitely hit capacity almost immediately.

FDA YouTube channel: https://www.youtube.com/channel/UC_giJ3 ... F1YfJdzzuQ

They should publish background materials by December 8.
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Re: Wuhan Flu Truth and Big Brother Narratives

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Thanksgiving should be a hoot this year
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Re: Wuhan Flu Truth and Big Brother Narratives

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Owl tends to be a bit gamy.
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Re: Wuhan Flu Truth and Big Brother Narratives

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Covid-19: Sweden's herd immunity strategy has failed, hospitals inundated

It looked like Sweden might be vindicated for its Covid-19 strategy. But in the past few weeks, the country of 10 million has been smashed by the virus.

With three words, Sweden's King Carl Gustaf captured the panic engulfing his country as it backflips on a controversial herd immunity strategy and coronavirus case numbers explode.

On Instagram, he wrote, simply: "Hold on tight!"

The message is echoing around the Nordic breakaway nation which, up until now, has run a distinctly different race to its neighbours who locked down hard when the pandemic breached its borders.

It signals a complete reversal of a policy that allowed Swedes to govern themselves in the hopes that life could go on as normal.

Life did carry on as normal and it looked like Sweden might be vindicated for its strategy. But in the past few weeks, the country of 10 million has been smashed by Covid-19.

There were 6000 cases in a single day last week and hospitalisations are rising faster than anywhere else in Europe.

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https://www.nzherald.co.nz/world/covid- ... OT7WJOLSU/
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Re: Wuhan Flu Truth and Big Brother Narratives

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AstraZeneca probes 'mistake' behind 90% COVID-19 vaccine efficacy
AstraZeneca is looking into why the accidental use of a half-dose primer vaccine appears to make its COVID-19 regimen more effective. The half-dose was given to some participants due to an error but is now AstraZeneca’s best hope of delivering efficacy comparable to mRNA vaccines.

Most participants in the late-phase analysis received a full dose of AZD1222. The efficacy in that group was 62%, well below the 90%-plus bar set by the Pfizer-BioNTech and Moderna vaccines. A far smaller cohort of subjects received a half-dose primer followed by a full-dose booster. The efficacy in that group was 90%. However, participants were never meant to receive a half-dose primer.

It was a mistake,” AstraZeneca Executive Vice President Mene Pangalos, Ph.D., told Reuters.

Pangalos said the mistake became apparent when researchers noticed the side effects seen in some participants were milder than expected. An attempt to explain the mild side effects revealed “they had underpredicted the dose of the vaccine by half,” Pangalos said. The participants went on to take a full booster shot.

The big efficacy question coming out of AstraZeneca’s data drop is whether the 90% figure is a true reflection of the protective power of the half-dose primer regimen. Only 2,741 subjects received the half-dose primer. Pfizer and Moderna enrolled more than 30,000 people in their phase 3 trials.

AstraZeneca was criticized for the data drop, with SVB Leerink analyst Geoffrey Porges saying “the suggestion by the inventors that the small sample given the lower priming dose was evidence of superior efficacy only brings discredit to the program.”

Ruud Dobber, president of AstraZeneca's U.S. business, told CNBC he expects regulators to focus on the half-dose regimen. The apparent efficacy of the half-dose regimen has led to speculation about why it would be more effective than giving two full doses. Dobber, who admitted the finding was “a little bit of a surprise to all of us,” offered one hypothesis.

“One of the potential hypotheses is that you’re priming the immune system with a relatively low dose or lower dose. As a consequence, the immune system is firing against this virus,” Dobber said.

It will take time to show whether the half-dose regimen really is far more effective and, if so, learn why. Dobber said AstraZeneca plans to do more research in the coming weeks to understand the mechanism.
So this half dose "primer" thing was entirely by accident. Funny, huh. It would be kinda cool if it turns out that an accident leads to a new scientific discovery. Progress often is made in directions that weren't anticipated.

The press release didn't mention that this was due to an accident. I'm still somewhat wary of the idea and wonder whether it might just be a statistical fluke, given the small sample size. But if it turns out to be real, maybe we will learn something interesting and useful about how to vaccinate. So many approaches to making a vaccine are being tried that we're bound to get some useful science out of this, as well as a means to end the current pandemic. Even failed attempts or those that are less efficacious may nonetheless yield important scientific findings.
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Re: Wuhan Flu Truth and Big Brother Narratives

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"vaccine" and "accident" should not be used in the same sentence.
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Things happen. That is why thorough review of data, methods, results, etc. are essential.
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Animal studies would quickly determine the best practice
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Maybe a small dose, then a half dose, then a huge slug of the virus

What’s the harm in trying?


On animals
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Press releases are one thing. Data, and how it is collected, however...

https://www.wired.com/story/the-astraze ... -to-snuff/
The problems start with the fact that Monday’s announcement did not present results from a single, large-scale, Phase 3 clinical trial, as was the case for earlier bulletins about the BNT-Pfizer and Moderna vaccines. Instead, Oxford-AstraZeneca’s data came out of two separate studies: one in the UK that began in May, and another in Brazil, which got started at the end of June. These two studies were substantially different from one another: They didn’t have standardized dosing schemes across the trials, for one thing, nor did they provide the same “control” injections to volunteers who were not getting the experimental Covid vaccine. The fact that they may have had to combine data from two trials in order to get a strong enough result raises the first red flag.
What ed said. Need to wait for the FDA sniff test...but the Oxford-AstraZeneca story appears to be somewhat dubious.
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Re: Wuhan Flu Truth and Big Brother Narratives

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Gary King
@kinggary
AstraZeneca: "What is there to disclose? It actually doesn’t matter whether it was done on purpose or not.” This is false. Experiments require investigator control over selection & assignment. AZ assigned treatment in an accidental (not random) subsample. Show us the data!
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ed wrote: Thu Nov 26, 2020 12:13 pm "vaccine" and "accident" should not be used in the same sentence.
It should not. If it happens anyway, should we forego attempting to learn what we can from it?
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I think the problem is that the data analysis didn't account for the dosing error until the error was discovered. In and of itself that may not be a problem, because clinical trial data is routinely re-evaluated. The article I linked to explains other concerns, such as the need to set the parameters of a clinical trial ahead of time, not changing them along the way. Regulatory agencies can and should hold all of the pharma companies respective feet to the fire, so to speak.
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Re: Wuhan Flu Truth and Big Brother Narratives

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Doctors say CDC should warn people the side effects from Covid vaccine shots won't be 'a walk in the park'
  • The CDC must be transparent about the side effects people may experience after getting their first shot of a coronavirus vaccine, doctors urged during a meeting Monday with CDC advisors.
  • Dr. Sandra Fryhofer said that both Pfizer's and Moderna's Covid-19 vaccines require two doses and she worries whether her patients will come back for a second dose because of potentially unpleasant side effects after the first shot.
  • Both companies acknowledged that their vaccines could induce side effects that are similar to symptoms associated with mild Covid-19, such as muscle pain, chills and headache.
https://www.cnbc.com/2020/11/23/covid-v ... park-.html
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I got those symptoms from the shingles vaccine both doses and I'll take those symptoms over severe coronavirus-induced illness any day of the week.
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↑ Or shingles. :)





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Re: Wuhan Flu Truth and Big Brother Narratives

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It's shady that they didn't mention any of this in the press release. I imagine that they were concerned that Pfizer and Moderna had already reported over 90% efficacy for their vaccine candidates, and that if they reported only 70% efficacy that it would be seen as a disappointment, even though 6 months ago that would have been seen as a smashing success. So they tried to spin the press release in a way that they could claim 90% efficacy even though that wasn't really well supported by the data and might be just a statistical fluke within a subset of the data.
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Yeah someone, somewhere failed at due diligence.
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Re: Wuhan Flu Truth and Big Brother Narratives

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Anaxagoras wrote: Fri Nov 27, 2020 1:28 am It's shady that they didn't mention any of this in the press release. I imagine that they were concerned that Pfizer and Moderna had already reported over 90% efficacy for their vaccine candidates, and that if they reported only 70% efficacy that it would be seen as a disappointment, even though 6 months ago that would have been seen as a smashing success. So they tried to spin the press release in a way that they could claim 90% efficacy even though that wasn't really well supported by the data and might be just a statistical fluke within a subset of the data.
Its called stock price manipulation and its very very illegal
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It's only illegal if you can prove it happened
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Sort of like election fraud
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Regular folks can post their opinions to the FDA: https://www.regulations.gov/document?D= ... -1898-0036
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https://www.reuters.com/article/idUKKBN2871A2
Suspected North Korean hackers have tried to break into the systems of British drugmaker AstraZeneca in recent weeks, two people with knowledge of the matter told Reuters, as the company races to deploy its vaccine for the COVID-19 virus. The hackers posed as recruiters on networking site LinkedIn and WhatsApp to approach AstraZeneca staff with fake job offers, the sources said. They then sent documents purporting to be job descriptions that were laced with malicious code designed to gain access to a victim’s computer.
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Are the vaccine makers going to hide the data and process from the world?
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robinson wrote: Fri Nov 27, 2020 6:01 pm Are the vaccine makers going to hide the data and process from the world?
They'll only show what they have to show. Won't reveal proprietary technology.
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Because it's not really a worldwide crisis at all
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I watched the entire presentation by Genevieve Briand, assistant program director of the Applied Economics master’s degree program at Hopkins, and it's checkmate motherfuckers.
After retrieving data on the CDC website, Briand compiled a graph representing percentages of total deaths per age category from early February to early September, which includes the period from before COVID-19 was detected in the U.S. to after infection rates soared.

Surprisingly, the deaths of older people stayed the same before and after COVID-19. Since COVID-19 mainly affects the elderly, experts expected an increase in the percentage of deaths in older age groups. However, this increase is not seen from the CDC data. In fact, the percentages of deaths among all age groups remain relatively the same.

“The reason we have a higher number of reported COVID-19 deaths among older individuals than younger individuals is simply because every day in the U.S. older individuals die in higher numbers than younger individuals,” Briand said.

Briand also noted that 50,000 to 70,000 deaths are seen both before and after COVID-19, indicating that this number of deaths was normal long before COVID-19 emerged. Therefore, according to Briand, not only has COVID-19 had no effect on the percentage of deaths of older people, but it has also not increased the total number of deaths.

These data analyses suggest that in contrast to most people’s assumptions, the number of deaths by COVID-19 is not alarming. In fact, it has relatively no effect on deaths in the United States.
https://web.archive.org/web/20201122214 ... o-covid-19
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Quick someone tell the hospitals that they are imagining their ICU overloads.
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That’s not what it means, nor did anyone but you say that

But the sarcasm tell was great
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Re: Wuhan Flu Truth and Big Brother Narratives

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Pyrrho wrote: Fri Nov 27, 2020 7:29 pm Quick someone tell the hospitals that they are imagining their ICU overloads.
Lockdown-weary Americans begin pandemic-changed holiday season

...

COVID-19 infections and hospitalizations have spiraled in recent weeks, prompting increasingly aggressive clamp-downs in many U.S. states as the country awaits government approval of vaccines developed by drug-makers Pfizer Inc and Moderna.

The U.S. Centers for Disease Control and Prevention will take a formal step early next week toward deciding who gets the first round of vaccine once it is approved, with an advisory committee meeting and vote on the “allocation of initial supplies of COVID-19 vaccine” on Tuesday, according to an agenda posted on its website.

Roughly 90,000 patients were being treated for COVID-19 in hospitals on Friday, a number that has doubled in the last month amid rising infections and is the highest since the pandemic began.
https://uk.reuters.com/article/health-c ... KKBN28729G

"It’s going to disappear. One day — it’s like a miracle — it will disappear. And from our shores, we — you know, it could get worse before it gets better. It could maybe go away. We’ll see what happens. Nobody really knows."

President Trump
February 27, 2020